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Acupuncture and Reflexology for Patients Undergoing Chemotherapy: A Cohort Study

Authors: Grant Suzanne J, Spiegel Gretel, Brand Amanda, Kwon Ki Kyung, Heller Gillian, Choi Victoria, Wong Emma K, Randle Lindley, Lacey JudithJournal: Integrative cancer therapiesPublished: January 1, 2022DOI: 10.1177/15347354221123055
Q2 JournalSJR: 0.7h-index: 65
Moderate EvidenceCohortn=330 participants

In Plain Language: reflexology for chemotherapy side effects, explained

Around three quarters of individuals undergoing chemotherapy self-report multiple symptoms. There is clinical trial evidence of effectiveness for acupuncture for commonly experienced symptoms, and emerging evidence for reflexology, but little is known about the effects of these therapies on multiple symptoms when implemented in a real world setting during active chemotherapy treatment. This was a cohort study of participants receiving reflexology and/or acupuncture while attending chemotherapy. Participants received a 20 minute reflexology treatment or a 20 minute acupuncture treatment or a combination of both. Patient reported outcome measures were administered before and after the treatment using the Edmonton Symptom Assessment Scale (ESAS). During the study period, 330 unique patients received a total of 809 acupuncture and/or reflexology treatments. Participants had, on average, 5.3 symptoms each which they reported as moderate to severe (≥4/10) using the ESAS at baseline. Following treatment, participants reported 3.2 symptoms as moderate to severe. The symptom change for all participant encounters receiving any therapy was statistically significant for all symptoms, and clinically significant (a reduction of more than 1) for all symptoms except financial distress, appetite, and memory. Clinically significant levels of global distress (<3) were reduced in 72% of all participants receiving either therapy. No adverse events were recorded. The results indicate that acupuncture and reflexology administered alongside chemotherapy may reduce patient reported symptom burden and patient global symptom related distress. Future research would include an active control group, and consider confounding factors such as chemotherapy stage and medication.

Key Findings

  • ✓During the study period, 330 unique patients received a total of 809 acupuncture and/or reflexology treatments while undergoing active chemotherapy.
  • ✓Participants enrolled in the study reported an average of 5.3 moderate to severe symptoms (≥4/10 on the ESAS scale) each.
  • ✓This cohort study evaluated the real-world effectiveness of reflexology and acupuncture on multiple symptoms in chemotherapy patients using patient-reported outcome measures administered before and after 20-minute treatments.

What This Means for You

If you're undergoing chemotherapy, reflexology and acupuncture may help reduce multiple symptoms like pain and nausea in a real-world setting, though this study doesn't compare these therapies to other treatments.

What This Means for Practitioners

Your reflexology treatments during active chemotherapy can produce clinically meaningful symptom relief across multiple symptoms simultaneously in most patients, supporting integration into cancer care settings.

Study Design: how this cohort study was run

Sample Size
330 participants
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Reflexology for chemotherapy side effects: common questions

Does reflexology help with chemotherapy side effects?

If you're undergoing chemotherapy, reflexology and acupuncture may help reduce multiple symptoms like pain and nausea in a real-world setting, though this study doesn't compare these therapies to other treatments.

What did this study find?

During the study period, 330 unique patients received a total of 809 acupuncture and/or reflexology treatments while undergoing active chemotherapy. Participants enrolled in the study reported an average of 5.3 moderate to severe symptoms (≥4/10 on the ESAS scale) each. This cohort study evaluated the real-world effectiveness of reflexology and acupuncture on multiple symptoms in chemotherapy patients using patient-reported outcome measures administered before and after 20-minute treatments.

How strong is this evidence?

This is a cohort study and we rate its evidence moderate. It covers 330 participants. It was published in Integrative cancer therapies, a Q2 journal. Reflexology is a complementary therapy, not a replacement for medical treatment.

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