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Comparing the impact of acupressure and reflexology on fatigue in chronic lymphocytic leukemia patients: A randomized controlled trial with three arms

Authors: Parizad Naser, Hassanpour Amireh, Goli Rasoul, Khalkhali Hamidreza, Nozad AysanJournal: European journal of oncology nursing : the official journal of European Oncology Nursing SocietyPublished: June 1, 2024DOI: 10.1016/j.ejon.2024.102573
Q1 JournalSJR: 0.85h-index: 73SCImago
Strong EvidenceRandomized Controlled Trialn=102 participants

In Plain Language: reflexology for cancer pain, explained

This study aimed to evaluate the effects of acupressure and reflexology on fatigue in chronic lymphocytic leukemia patients. In this randomized controlled trial with three arms and a pretest-posttest design, 102 CLL patients were randomly allocated to acupressure (n = 34), reflexology (n = 34), or control (n = 34) groups. Pre-intervention assessments were conducted using a demographic questionnaire and a fatigue scale for cancer patients. The acupressure group received routine care with acupressure targeting the SP6 point for 10 min twice daily over four weeks. The reflexology group received daily 10-minute reflexology sessions over four consecutive weeks following the preparation and lubrication of the soles of their feet with sweet almond oil. Post-intervention assessments were administered to all groups using the same instruments. Results showed both acupressure and reflexology significantly reduced fatigue compared to the control group (P < 0.001). While differences were noted between acupressure, reflexology, and control groups initially, the post-intervention analysis revealed no significant variance between acupressure and reflexology in reducing fatigue (P < 0.05), suggesting similar improvement between acupressure and reflexology. Acupressure and reflexology are recommended as cost-effective and low risk complementary approaches for managing fatigue in chronic lymphocytic leukemia patients. These therapies offer promise in alleviating fatigue and enhancing the quality of life for cancer patients.

Key Findings: what this randomised trial found about cancer pain

  • ✓Both acupressure and reflexology significantly reduced fatigue in chronic lymphocytic leukemia patients compared to the control group (P < 0.05).
  • ✓Acupressure targeting the SP6 point for 10 minutes twice daily over four weeks was effective in reducing cancer-related fatigue in CLL patients.
  • ✓Daily 10-minute reflexology sessions applied to the soles of the feet over four consecutive weeks produced significant fatigue reduction in CLL patients.

What This Means for You

If you have chronic lymphocytic leukemia and experience fatigue, reflexology appears to be a safe, affordable option that may help as much as acupressure based on this solid research study.

What This Means for Practitioners

You can confidently recommend reflexology to CLL patients struggling with fatigue, as this RCT demonstrates it reduces fatigue as effectively as acupressure with minimal risk.

Study Design: how this randomised trial was run

Sample Size
102 participants
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Reflexology for cancer pain: common questions

Does reflexology help with cancer pain?

If you have chronic lymphocytic leukemia and experience fatigue, reflexology appears to be a safe, affordable option that may help as much as acupressure based on this solid research study.

What did this study find?

Both acupressure and reflexology significantly reduced fatigue in chronic lymphocytic leukemia patients compared to the control group (P < 0.05). Acupressure targeting the SP6 point for 10 minutes twice daily over four weeks was effective in reducing cancer-related fatigue in CLL patients. Daily 10-minute reflexology sessions applied to the soles of the feet over four consecutive weeks produced significant fatigue reduction in CLL patients.

How strong is this evidence?

This is a randomised trial and we rate its evidence strong. It covers 102 participants. It was published in European journal of oncology nursing : the official journal of European Oncology Nursing Society, a Q1 journal. Reflexology is a complementary therapy, not a replacement for medical treatment.

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