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Complementary Therapies for Patients with Cancer: Reflexology and Relaxation in Integrative Palliative Care. A Randomized Controlled Comparative Study

Authors: Mantoudi Alexandra, Parpa Efi, Tsilika Eleni, Batistaki Chrysanthi, Nikoloudi Maria, Kouloulias Vassilios, Kostopoulou Sotiria, Galanos Antonis, Mystakidou KyriakiJournal: Journal of alternative and complementary medicine (New York, N.Y.)Published: September 1, 2020DOI: 10.1089/acm.2019.0402
Q2 JournalSJR: 0.55h-index: 90
Strong EvidenceRandomized Controlled Trialn=88 participants

In Plain Language: reflexology for cancer pain, explained

Objectives: Comparison of the effects of reflexology and relaxation on pain, anxiety, and depression, and quality of life (QoL) of patients with cancer. Design: A stratified random sample was selected, using an experimental design. Location: An outpatient Palliative Care Unit in Attica, Greece. Subjects: 88 patients suffering with cancer. Interventions: The sample was randomly divided into two equal groups, a reflexology and a relaxation group. The number of interventions for both groups was six 30-min weekly sessions. Outcome measures: The Greek Brief Pain Inventory (G-BPI) was used to measure pain, the Greek Hospital Anxiety and Depression Scale for screening anxiety and depression, and finally the Short Form Health Survey was used to measure QoL. Measurements of the above tools were taken three times in both groups as follows: preintervention, at fourth and at sixth week of intervention. Results: Anxiety and depression for both groups exhibited a statistically significant decrease during the observation period (p 2 > 0.25) but at the sixth week, there was a more significant decrease in the reflexology group compared with the relaxation group (p = 0.062, η2 = 0.044 vs. p = 0.005, η2 = 0.096 for anxiety), (p = 0.006, η2 = 0.094 vs. p = 0.001, η2 = 0.138 for depression). QoL physical and mental component measurements were significantly greater for the reflexology group (p 2 = 0.168 and p = 0.017, η2 = 0.071, respectively). The baseline-to-sixth week G-BPI measurements were markedly decreased for the reflexology group (p = 0.207, η2 = 0.020). Conclusions: Both interventions, relaxation and reflexology, seemed to be effective in decreasing anxiety and depression in patients with cancer. However, reflexology was found to be more effective in

Key Findings: what this randomised trial found about cancer pain

  • ✓Both reflexology and relaxation interventions produced statistically significant decreases in anxiety and depression among cancer patients.
  • ✓The study compared the effects of six weekly 30-minute sessions of reflexology versus relaxation on pain, anxiety, depression, and quality of life in 88 cancer patients using validated measurement scales.
  • ✓Outcomes were measured at three time points: before intervention, at the fourth week, and at the sixth week of treatment.

What This Means for You

If you have cancer and are considering reflexology, this study suggests it may help reduce anxiety and depression similarly to relaxation therapy, though the evidence is moderately strong and benefits are modest.

What This Means for Practitioners

This RCT provides evidence that reflexology can be integrated into palliative cancer care as an effective complementary therapy for anxiety and depression alongside conventional relaxation approaches.

Study Design: how this randomised trial was run

Sample Size
88 participants
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Reflexology for cancer pain: common questions

Does reflexology help with cancer pain?

If you have cancer and are considering reflexology, this study suggests it may help reduce anxiety and depression similarly to relaxation therapy, though the evidence is moderately strong and benefits are modest.

What did this study find?

Both reflexology and relaxation interventions produced statistically significant decreases in anxiety and depression among cancer patients. The study compared the effects of six weekly 30-minute sessions of reflexology versus relaxation on pain, anxiety, depression, and quality of life in 88 cancer patients using validated measurement scales. Outcomes were measured at three time points: before intervention, at the fourth week, and at the sixth week of treatment.

How strong is this evidence?

This is a randomised trial and we rate its evidence strong. It covers 88 participants. It was published in Journal of alternative and complementary medicine (New York, N.Y.), a Q2 journal. Reflexology is a complementary therapy, not a replacement for medical treatment.

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