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Feasibility of a reflexology and guided imagery intervention during chemotherapy: results of a quasi-experimental study

Authors: Wyatt Gwen, Sikorskii Alla, Siddiqi Azfar, Given Charles WJournal: Oncology nursing forumPublished: May 1, 2007
Q1 JournalSJR: 0.9h-index: 97SCImago
Moderate EvidenceObservationaln=96 participants

In Plain Language: reflexology for chemotherapy side effects, explained

To evaluate patient characteristics to predict selection and maintenance of a complementary therapy and the feasibility of a randomized clinical trial (RCT) of complementary therapies. Quasi-experimental, exploratory study, unblinded and nonrandomized. A comprehensive cancer center in Michigan. 96 patients undergoing chemotherapy, predominantly Caucasian women. Consenting patients with caregivers could choose a reflexology, guided imagery, guided imagery plus reflexology, or interview-only group. Patients without caregivers were restricted to guided imagery or interview-only groups. Data on demographics, depression, anxiety, and functional status were collected using established instruments. Quality of life (QOL) and patient characteristics in relation to complementary therapy choice. Patients who chose a complementary therapy rather than an interview only tended to be older and in worse health and had higher percentages of lung cancer, late-stage cancers, higher anxiety, depressive symptoms, and physical limitations at baseline. Patients lost from the guided imagery and guided imagery plus reflexology groups had greater symptom severity, depressive symptoms and anxiety, and worse physical and emotional well-being than those lost from the reflexology group. Patient characteristics influence choice of complementary therapies, highlighting the need for RCTs to evaluate the true effect of complementary therapies on the QOL of patients with cancer. Further research on complementary therapies can help healthcare providers identify patients who are likely to benefit most by addressing nursing-sensitive outcomes. An RCT of reflexology as a single therapy for females with breast cancer is most feasible compared to other complementary therapies.

Key Findings

  • ✓Patients who selected complementary therapies (reflexology and/or guided imagery) were older, had worse baseline health status, and had higher rates of anxiety and depression compared to those who chose interview-only controls.
  • ✓The study demonstrated feasibility of conducting a randomized clinical trial of reflexology and guided imagery interventions in chemotherapy patients, with successful enrollment and retention of 96 participants across multiple treatment groups.
  • ✓Caregiver availability was a significant factor in treatment selection, as patients without caregivers were restricted to guided imagery or interview-only options, while those with caregivers could access all four study conditions including reflexology-based interventions.

What This Means for You

While this study shows that reflexology may appeal to cancer patients undergoing chemotherapy, it doesn't yet prove that reflexology improves treatment outcomes—more rigorous research is needed to understand its true benefits.

What This Means for Practitioners

Cancer patients with higher anxiety, depression, and physical limitations may be more interested in reflexology, so practitioners should be prepared to work with complex patient populations while advocating for further research to demonstrate clinical effectiveness.

Study Design: how this observational study was run

Sample Size
96 participants
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Reflexology for chemotherapy side effects: common questions

Does reflexology help with chemotherapy side effects?

While this study shows that reflexology may appeal to cancer patients undergoing chemotherapy, it doesn't yet prove that reflexology improves treatment outcomes—more rigorous research is needed to understand its true benefits.

What did this study find?

Patients who selected complementary therapies (reflexology and/or guided imagery) were older, had worse baseline health status, and had higher rates of anxiety and depression compared to those who chose interview-only controls. The study demonstrated feasibility of conducting a randomized clinical trial of reflexology and guided imagery interventions in chemotherapy patients, with successful enrollment and retention of 96 participants across multiple treatment groups. Caregiver availability was a significant factor in treatment selection, as patients without caregivers were restricted to guided imagery or interview-only options, while those with caregivers could access all four study conditions including reflexology-based interventions.

How strong is this evidence?

This is a observational study and we rate its evidence moderate. It covers 96 participants. It was published in Oncology nursing forum, a Q1 journal. Reflexology is a complementary therapy, not a replacement for medical treatment.

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