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The effect of hand reflexology massage on pain and hemodynamic parameters during endotracheal suctioning: A double-blind, randomized, 2 × 2 crossover study

Authors: Yilmaz İlkin, Göktuna Gizem, Arslan Gülşah Gürol, Özden DilekJournal: Explore (New York, N.Y.)Published: January 1, 2026DOI: 10.1016/j.explore.2025.103313
Q2 JournalSJR: 0.5h-index: 55
Limited EvidenceRandomized Controlled Trialn=24 participants

In Plain Language: reflexology for high blood pressure, explained

Endotracheal suctioning is a common painful procedure in intensive care. Reflexology massage, a non-pharmacological pain relief method, hasn't been studied in this context. To examine the effect of reflexology hand massage and placebo hand massage on pain and hemodynamic parameters related to endotracheal suctioning. This double-blind, randomized, 2 × 2 crossover controlled trial included 24 intubated ICU patients. Massage was applied to both hands of individuals in the reflexology and placebo groups for 10 min on each hand, for a total of 20 min over two consecutive days. Data were collected using the Patient Demographic Information Form, Hemodynamic Parameters and Pain Monitoring Form, Critical Care Pain Observation Tool. The data were analyzed using pairwise and triple group comparison tests for dependent and independent groups. The pain scores of patients who received reflexology on the first and second day before, during, and after suctioning were 0.33±0.65, 1.83±1.02, 0.00±0.00, and 0.58±0.90, 1.66±1.07, 0.00±0.00, respectively. The pain scores of patients who received placebo massage on the first and second day were recorded as 1.83±1.46, 3.58±0.99, 0.66±0.65, and 1.33±0.98, 3.08±0.79, 0.75±0.62, respectively (p < 0.05 between and within groups). After suctioning, a decrease in diastolic blood pressure and respiratory rate, along with an increase in tidal volume, was observed in the reflexology group (p < 0.05). Hand reflexology massage is effective in alleviating suction-related pain and improving the patient's hemodynamics. Hand reflexology massage may be recommended for reducing suction pain, providing comfort, and improving hemodynamic instability in intensive care patients.

Key Findings: what this randomised trial found about high blood pressure

  • ✓Hand reflexology massage significantly reduced pain scores in intubated ICU patients during endotracheal suctioning compared to placebo massage.
  • ✓The study demonstrated that reflexology massage applied for 20 minutes (10 minutes per hand) provided non-pharmacological pain relief for a common painful ICU procedure.
  • ✓Pain reduction from reflexology was maintained across multiple days of treatment, with consistent effects observed on both the first and second day of the intervention.

What This Means for You

Hand reflexology may help reduce pain during medical procedures in hospital settings, though this finding is based on a small study and more research is needed to confirm the results.

What This Means for Practitioners

This study provides preliminary evidence that reflexology hand massage can measurably reduce pain and improve hemodynamic stability during medical procedures, suggesting potential applications in clinical care settings.

Study Design: how this randomised trial was run

Sample Size
24 participants
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Reflexology for high blood pressure: common questions

Does reflexology help with high blood pressure?

Hand reflexology may help reduce pain during medical procedures in hospital settings, though this finding is based on a small study and more research is needed to confirm the results.

What did this study find?

Hand reflexology massage significantly reduced pain scores in intubated ICU patients during endotracheal suctioning compared to placebo massage. The study demonstrated that reflexology massage applied for 20 minutes (10 minutes per hand) provided non-pharmacological pain relief for a common painful ICU procedure. Pain reduction from reflexology was maintained across multiple days of treatment, with consistent effects observed on both the first and second day of the intervention.

How strong is this evidence?

This is a randomised trial and we rate its evidence limited. It covers 24 participants. It was published in Explore (New York, N.Y.), a Q2 journal. Reflexology is a complementary therapy, not a replacement for medical treatment.

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