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Use of reflexology foot massage to reduce anxiety in hospitalized cancer patients in chemotherapy treatment: methodology and outcomes

Authors: Quattrin R, Zanini A, Buchini S, Turello D, Annunziata M A, Vidotti C, Colombatti A, Brusaferro SJournal: Journal of nursing managementPublished: March 1, 2006
Limited EvidenceRandomized Controlled Trialn=30 participants

In Plain Language: reflexology for anxiety, explained

To examine the effectiveness of reflexology foot massage in hospitalized cancer patients undergoing second or third chemotherapy cycles. Since the late-1970s, studies have been conducted to assess the efficacy of behavioural and relaxation approaches in controlling nausea/vomiting, anxiety and other side-effects associated with chemotherapy. The study consisted of 30 patients being admitted to the oncology unit at a Scientific Research Hospital in Italy. Only 15 of the 30 participants received therapeutic massage. The subjects' self-reports of anxiety (measured by the Spielberger State-Trait Anxiety Inventory) were recorded before, after and 24 hours after the intervention. There was an average decrease of 7.9 points on the state-anxiety scale in the treatment group and of 0.8 points in the control group (P < 0.0001). Reflexology foot massage can be considered a support treatment used in combination with traditional medical treatments and executed by an expert, qualified person to help cancer patients receiving chemotherapy feel better and also cope better with their disease.

Key Findings: what this randomised trial found about anxiety

  • ✓Reflexology foot massage produced an average decrease of 7.9 points on the state-anxiety scale in hospitalized cancer patients undergoing chemotherapy, compared to only 0.8 points in the control group (P < 0.0001).
  • ✓The anxiety-reducing effects of reflexology foot massage were measured using the Spielberger State-Trait Anxiety Inventory before the intervention, immediately after, and 24 hours post-treatment.
  • ✓Reflexology foot massage can serve as a supportive complementary treatment alongside traditional medical therapies when administered by qualified, trained practitioners in cancer patients undergoing chemotherapy.

What This Means for You

Reflexology may help reduce anxiety during chemotherapy, but this small study shows promise rather than definitive proof—discuss it with your medical team as a complementary support alongside standard cancer care.

What This Means for Practitioners

This study supports reflexology as an adjunctive anxiety-reduction tool in oncology settings, but positioning it as a professional complement to medical treatment—not a replacement—strengthens credibility with healthcare teams.

Study Design: how this randomised trial was run

Sample Size
30 participants
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Reflexology for anxiety: common questions

Does reflexology help with anxiety?

Reflexology may help reduce anxiety during chemotherapy, but this small study shows promise rather than definitive proof—discuss it with your medical team as a complementary support alongside standard cancer care.

What did this study find?

Reflexology foot massage produced an average decrease of 7.9 points on the state-anxiety scale in hospitalized cancer patients undergoing chemotherapy, compared to only 0.8 points in the control group (P < 0.0001). The anxiety-reducing effects of reflexology foot massage were measured using the Spielberger State-Trait Anxiety Inventory before the intervention, immediately after, and 24 hours post-treatment. Reflexology foot massage can serve as a supportive complementary treatment alongside traditional medical therapies when administered by qualified, trained practitioners in cancer patients undergoing chemotherapy.

How strong is this evidence?

This is a randomised trial and we rate its evidence limited. It covers 30 participants. It was published in Journal of nursing management. Reflexology is a complementary therapy, not a replacement for medical treatment.

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