Skip to main content

Reflexology Research & Science

Does reflexology work? The honest answer from 808 peer-reviewed studies: the evidence is mixed and mostly early-stage. 245 are randomized controlled trials and 221 are systematic reviews or meta-analyses. The strongest signals are for relaxation, anxiety, and pain, not for curing disease. Every study is below, graded by evidence strength and pulled from PubMed.

808 studies · page 22 of 68

Effects of aroma self-foot reflexology on peripheral neuropathy, peripheral skin temperature, anxiety, and depression in gynaecologic cancer patients undergoing chemotherapy: A randomised controlled trial.

Gie Ok Noh, Kyung Sook ParkEuropean journal of oncology nursing : the official journal of European Oncology Nursing Society2020

Researchers tested whether foot reflexology combined with aromatherapy could help cancer patients undergoing chemotherapy. They randomly assigned gynecologic cancer patients to receive either aroma self-foot reflexology or standard care, and measured effects on nerve pain, skin temperature, anxiety, and depression.

moderate evidenceRCTQ2 JournalAnxietyDepressionPeripheral NeuropathyChemotherapy Side EffectsCancer Pain Management

Comparing the effects of reflexology and relaxation on fatigue in women with multiple sclerosis.

Fatemeh Nazari, Mozhgan Soheili Shahreza, Vahid Shaygannejad, Mahboubeh ValianiIranian journal of nursing and midwifery research2015

Researchers compared reflexology treatment to relaxation techniques in women with multiple sclerosis to see which approach better reduced fatigue. Both treatments showed benefits for reducing fatigue symptoms, suggesting that reflexology may be a useful complementary therapy for MS-related tiredness.

moderate evidenceRCTQ2 Journal

A comparison of the effects of reflexology and relaxation on pain in women with multiple sclerosis.

Fatemeh Nazari, Mozhgan Soheili, SayedMohsen Hosseini, Vahid ShaygannejadJournal of complementary & integrative medicine2016
moderate evidenceRCTQ2 Journal

The Effect of Acupressure on Blood Pressure Level and Pulse Rate in Individuals With Essential Hypertension: A Randomized Controlled Trial.

Sevil Biçer, Ayla Ünsal, Sultan Taşcı, Gökçe Demir, Yasemin Şadiye CeyhanHolistic nursing practice2021

This study tested whether acupressure (applying pressure to specific points on the body) could help lower blood pressure and heart rate in people with high blood pressure. Researchers randomly assigned participants to receive either acupressure treatment or standard care, then measured their blood pressure and pulse rates to see if acupressure made a difference.

moderate evidenceRCTQ2 JournalHigh Blood Pressure

The effects of auricular acupressure on blood pressure, stress, and sleep in elders with essential hypertension: a randomized single-blind sham-controlled trial.

Bomi Kim, Hyojung ParkEuropean journal of cardiovascular nursing2023

Researchers tested whether pressing specific points on the ear (auricular acupressure) could help older adults with high blood pressure. They compared real ear acupressure to a fake treatment and measured changes in blood pressure, stress levels, and sleep quality.

moderate evidenceRCTQ2 JournalChronic StressInsomniaHigh Blood Pressure

The Effect of Reflexology on the Pain-Insomnia-Fatigue Disturbance Cluster of Breast Cancer Patients During Adjuvant Radiation Therapy.

Ricardo Tarrasch, Narin N Carmel-Neiderman, Sarah Ben-Ami, Bella Kaufman, Raphi Pfeffer, Merav Ben-David et al.Journal of alternative and complementary medicine (New York, N.Y.)2018

Researchers tested whether reflexology could help breast cancer patients undergoing radiation therapy who were experiencing pain, insomnia, and fatigue. The study compared patients who received reflexology treatment to a control group to see if reflexology reduced these three interconnected symptoms.

moderate evidenceRCTQ2 JournalInsomniaCancer Pain Management

Effect of reflexology on ankle brachial index, diabetic peripheral neuropathy, and glycemic control in older adults with diabetes: A randomized controlled trial.

Saadet Can Cicek, Seyma Demir, Dilek Yilmaz, Sedat YildizComplementary therapies in clinical practice2021

Researchers tested whether reflexology—a massage technique applied to the feet—could help older adults with diabetes improve their blood sugar control, nerve damage, and blood vessel function. The study compared people who received reflexology treatments to a control group and measured changes in these health markers over time.

moderate evidenceRCTQ2 JournalPeripheral NeuropathyDiabetes (Supportive)

Foot reflexology in feet impairment of people with type 2 diabetes mellitus: randomized trial.

Natália Chantal Magalhães da Silva, Érika de Cássia Lopes Chaves, Emilia Campos de Carvalho, Leonardo César Carvalho, Denise Hollanda IunesRevista latino-americana de enfermagem2017

Researchers tested whether foot reflexology could help improve foot problems in people with type 2 diabetes by randomly assigning participants to receive reflexology or standard care. The study measured changes in foot sensation, pain, and other markers of foot health over time.

moderate evidenceRCTQ2 JournalDiabetes (Supportive)

Impact of music therapy and hand massage in the pediatric intensive care unit on pain, fear and stress: Randomized controlled trial.

Dilek Küçük Alemdar, Azime Bulut, Gamze YilmazJournal of pediatric nursing2023

This study explored how music therapy and hand massage can reduce pain, fear, and stress in adolescents aged 12 to 18 who are receiving treatment in a pediatric intensive care unit. The results showed that both therapies significantly decreased pain and fear levels during blood-drawing procedures compared to standard care, which is important for improving the comfort of young patients in high-stress medical situations.

moderate evidenceRCTn=99Q2 JournalChronic Stress

The Effect of Foot Reflexology Applied Before Coronary Angiography and Percutaneous Transluminal Coronary Angioplasty on Anxiety, Stress, and Cortisol Levels of Individuals: A Randomized Controlled Trial.

Birgül Vural Doğru, Fisun ŞenuzunAykar, Yasemin Yıldırım, Oğuz Yavuzgil, Eser Sözmen, Hikmet MemmedovThe Journal of cardiovascular nursing2021

A study investigated the effects of foot reflexology on anxiety and stress levels in patients undergoing coronary angiography and percutaneous transluminal coronary angioplasty. The findings revealed that patients who received reflexology before these procedures experienced significantly lower anxiety, stress, and cortisol levels compared to those who did not. This demonstrates the potential of reflexology as a therapeutic option to alleviate anxiety in medical settings.

moderate evidenceRCTn=116Q2 JournalAnxietyChronic Stress

Massage During Pregnancy and Postpartum.

Sarah L Pachtman Shetty, Sarah FogartyClinical obstetrics and gynecology2021

A study focused on the effects of massage therapy during pregnancy and labor. The researchers found that massage can effectively reduce anxiety and pain in pregnant women, making it a valuable alternative to medications during childbirth. This underscores the importance of integrating non-pharmacological methods like massage to enhance maternal wellbeing.

moderate evidenceRCTQ2 JournalPregnancy Discomfort

The mechanisms of manual therapy in the treatment of musculoskeletal pain: a comprehensive model.

Joel E Bialosky, Mark D Bishop, Don D Price, Michael E Robinson, Steven Z GeorgeManual therapy2009

A recent study investigated how manual therapy (MT) helps treat musculoskeletal pain. Researchers proposed a model showing that a mechanical force from MT triggers a series of neurophysiological responses that can lead to pain relief. Understanding these mechanisms could help improve future treatment methods and outcomes for patients experiencing pain.

moderate evidenceRCTQ2 Journal

Does reflexology work? Common questions

Is reflexology scientifically proven?

No. The most careful reviews conclude reflexology isn't a proven treatment for any specific medical condition. What the research more consistently supports is relaxation and short-term relief of anxiety and pain. We track 808 studies here, graded by evidence strength, so you can judge for yourself.

Does reflexology actually work?

It depends what you mean. For curing or treating a disease, the evidence doesn't support it. For helping people relax and feel less anxious or in less pain during a session, a number of small studies are positive, including 245 randomized controlled trials and 221 systematic reviews or meta-analyses in this library.

Is reflexology a pseudoscience?

Reflexology's core idea, that specific points on the feet map to distant organs, isn't backed by anatomy or physiology, and that's why critics call it pseudoscience. The relaxation and comfort people feel during a session are real, though. It's best understood as a complementary relaxation practice, not a medical treatment.

What is reflexology best supported for?

The strongest and most consistent evidence is for relaxation and short-term reduction in anxiety and pain, plus some cancer-care symptoms like nausea and fatigue. Evidence for treating specific diseases is weak. Use the evidence-strength filter to sort studies by how solid they are.

Know of a study we're missing?

Know a study we are missing? Help us keep the research library complete.

Submit a Study