Skip to main content

Reflexology Research & Science

Does reflexology work? The honest answer from 808 peer-reviewed studies: the evidence is mixed and mostly early-stage. 245 are randomized controlled trials and 221 are systematic reviews or meta-analyses. The strongest signals are for relaxation, anxiety, and pain, not for curing disease. Every study is below, graded by evidence strength and pulled from PubMed.

808 studies · page 46 of 68

Acupuncture and Reflexology for Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer.

Idan Ben-Horin, Peretz Kahan, Larisa Ryvo, Moshe Inbar, Shahar Lev-Ari, Ravit GevaIntegrative cancer therapies2018

This study examined whether acupuncture and reflexology could help breast cancer patients experiencing nerve pain and numbness (peripheral neuropathy) caused by chemotherapy. The research looked at how these complementary therapies affected symptoms in cancer patients dealing with this common side effect.

limited evidenceObservationalQ2 JournalPeripheral NeuropathyChemotherapy Side EffectsCancer Pain Management

Comparison of Two Manual Therapy Programs, including Tendon Gliding Exercises as a Common Adjunct, While Managing the Participants with Chronic Carpal Tunnel Syndrome.

Fauzia Javed Sheereen, Bibhuti Sarkar, Pallavi Sahay, Mohammad Abu Shaphe, Ahmad H Alghadir, Amir Iqbal et al.Pain research & management2022
moderate evidenceRCTCarpal Tunnel Syndrome

Reflexology treatment relieves symptoms of multiple sclerosis: a randomized controlled study.

I Siev-Ner, D Gamus, L Lerner-Geva, A AchironMultiple sclerosis (Houndmills, Basingstoke, England)2003

Researchers gave some people with multiple sclerosis reflexology treatments while others received no treatment, then tracked how their symptoms changed. The study found that reflexology appeared to reduce multiple sclerosis symptoms, suggesting it may offer some benefit as a complementary therapy.

moderate evidenceRCT

Effects of the Right Carotid Sinus Compression Technique on Blood Pressure and Heart Rate in Medicated Patients with Hypertension.

Angélica María Campón-Checkroun, Agustín Luceño-Mardones, Inmaculada Riquelme, Jesús Oliva-Pascual-Vaca, François Ricard, Ángel Oliva-Pascual-VacaJournal of alternative and complementary medicine (New York, N.Y.)2019

This study examined whether a specific carotid sinus compression technique applied in reflexology could affect blood pressure and heart rate in people already taking blood pressure medications. The researchers measured these vital signs before and after the treatment to see if the technique had any measurable effects.

limited evidenceObservationalQ2 JournalSinus Congestion / SinusitisHigh Blood Pressure

Impact of classic massage on blood pressure in patients with clinically diagnosed hypertension.

Robert WalaszekJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2015

Researchers studied whether classic massage could help lower blood pressure in people diagnosed with high blood pressure. The study examined the effects of massage treatment on this patient group, though specific results are not detailed in the provided information.

limited evidenceObservationalQ2 JournalHigh Blood Pressure

Management of prostatitis.

H S Gurunadha Rao Tunuguntla, C P EvansProstate cancer and prostatic diseases2003

This paper reviews current approaches to diagnosing and treating prostatitis, a condition involving inflammation or infection of the prostate gland. The authors summarize medical management strategies based on clinical evidence and experience. This is a review article rather than a clinical trial testing a specific treatment.

limited evidenceObservationalQ2 Journal

Effectiveness of a manual therapy protocol based on articulatory techniques in migraine patients. A randomized controlled trial.

Elena Muñoz-Gómez, Marta Inglés, Pilar Serra-Añó, Gemma V Espí-LópezMusculoskeletal science & practice2021
moderate evidenceRCTMigraines

Effect of applying reflexology massage on nitroglycerin-induced migraine-type headache: A placebo-controlled clinical trial.

Nima Imani, Shams Aldin Shams, Moloud Radfar, Haleh Ghavami, Hamid Reza KhalkhaliAgri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology2019

Researchers tested whether reflexology massage could reduce migraine-type headaches triggered by nitroglycerin in a controlled trial with a placebo group. The study compared reflexology treatment to a placebo control to see if the massage technique had real effects on this specific type of headache.

moderate evidenceRCTMigrainesTension Headaches

Integrative Therapies in Cancer Care: An Update on the Guidelines.

Krisstina Gowin, Meri Muminovic, Suzanna M Zick, Richard T Lee, Christina Lacchetti, Ashwin MehtaAmerican Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting2024

A recent study explored how reflexology can help manage anxiety and depression in cancer patients. The findings indicated that reflexology is an effective complementary therapy to improve emotional well-being during and after cancer treatment. This research highlights the importance of integrating alternative therapies into standard care for better outcomes.

moderate evidenceRCTCancer Pain ManagementAnxietyDepression

Neuropathic Pain.

Amanda Macone, James A D OtisSeminars in neurology2019

This study explored the effectiveness of reflexology as a treatment for managing neuropathic pain, which is often difficult to treat. The findings suggest that while reflexology can be used as part of a broader pain management strategy, more robust studies are necessary to establish its overall efficacy. Understanding these results is crucial for both patients and healthcare providers as they consider non-pharmacologic options.

limited evidenceObservationalQ2 JournalPeripheral Neuropathy

The effectiveness of mobilization with movement on pain, balance and function following acute and sub acute inversion ankle sprain - A randomized, placebo controlled trial.

Neha Gogate, Kiran Satpute, Toby HallPhysical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine2021

This study examined the effects of mobilization with movement (MWM) on patients with acute and sub-acute ankle sprains. The researchers found that MWM significantly reduced pain and improved ankle mobility and function, which is important for patients recovering from ankle injuries.

moderate evidenceRCTn=32

Comparison of effectiveness of supervised exercise program and Cyriax physiotherapy in patients with tennis elbow (lateral epicondylitis): a randomized clinical trial.

Rajadurai Viswas, Rejeeshkumar Ramachandran, Payal Korde AnantkumarTheScientificWorldJournal2012

A study was conducted to compare the effectiveness of a supervised exercise program with Cyriax physiotherapy for treating tennis elbow. The results showed that both treatments were helpful in reducing pain and improving function, but the supervised exercise program was more effective. This finding is important as it suggests a preferred treatment option for individuals suffering from this condition.

moderate evidenceRCTn=20

Does reflexology work? Common questions

Is reflexology scientifically proven?

No. The most careful reviews conclude reflexology isn't a proven treatment for any specific medical condition. What the research more consistently supports is relaxation and short-term relief of anxiety and pain. We track 808 studies here, graded by evidence strength, so you can judge for yourself.

Does reflexology actually work?

It depends what you mean. For curing or treating a disease, the evidence doesn't support it. For helping people relax and feel less anxious or in less pain during a session, a number of small studies are positive, including 245 randomized controlled trials and 221 systematic reviews or meta-analyses in this library.

Is reflexology a pseudoscience?

Reflexology's core idea, that specific points on the feet map to distant organs, isn't backed by anatomy or physiology, and that's why critics call it pseudoscience. The relaxation and comfort people feel during a session are real, though. It's best understood as a complementary relaxation practice, not a medical treatment.

What is reflexology best supported for?

The strongest and most consistent evidence is for relaxation and short-term reduction in anxiety and pain, plus some cancer-care symptoms like nausea and fatigue. Evidence for treating specific diseases is weak. Use the evidence-strength filter to sort studies by how solid they are.

Know of a study we're missing?

Know a study we are missing? Help us keep the research library complete.

Submit a Study