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Reflexology Research & Science

Does reflexology work? The honest answer from 808 peer-reviewed studies: the evidence is mixed and mostly early-stage. 245 are randomized controlled trials and 221 are systematic reviews or meta-analyses. The strongest signals are for relaxation, anxiety, and pain, not for curing disease. Every study is below, graded by evidence strength and pulled from PubMed.

808 studies · page 47 of 68

Complementary therapy and alternative medicine: effects on induction of labour and pregnancy outcome in low risk post-dates women

Koh Li Mei, Percival Beccy, Pauley Tara, Pathak SangeetaHeliyon2019

Complementary therapy and Alternative medicine (CAM) is used worldwide for many ailments and is a popular option amongst pregnant women for general wellbeing and managing symptoms. Many studies investigating the use of CAM in the antenatal and intrapartum period have been conducted however there is a lack of evidence regarding its effects on induction of labour and delivery. We established a post-dates clinic comprising of an antenatal check and CAM for low risk pregnant women to determine the impact of CAM on these outcomes. This was a cohort study with convenience sampling. A total of 1044 women were included. 397 received a combination of three CAM techniques (acupressure, reflexology and aromatherapy) and 647 women received standard clinical practice. The primary outcome was rate of induction of labour and secondary outcomes such as rates for epidural, length of labour, oxytocin use for induction or augmentation of labour, mode of delivery, blood loss during delivery, postpartum haemorrhage, significant perineal trauma, shoulder dystocia and admission of the baby to a special care unit were analysed. CAM did not have an effect on rates of induction of labour in nulliparous or multiparous women attending the post-dates clinic. However, we noted that nulliparous women who received CAM had shorter labours (mean 8.4 vs 10 h, p = 0.0002), less oxytocin augmentation (23% vs 35%, p = 0.0002), lower epidural rates (41% vs 50.5%, p = 0.02) and reduced blood loss regardless of mode of delivery (mean reduction 82ml, p = 0.03; 95%CI = -159 to -5). There were no significant differences in secondary outcomes when CAM was used in multiparous women apart from a 5.3 times increased risk of significant perineal trauma (6% vs 2%, p = 0.004) and those who had their labours induced after CAM had a higher risk of requiring an emergency caesarean section (5% vs 1%, p = 0.012). There was no difference on shoulder dystocia and neonatal admissions rates with CAM. There is no reduction

moderate evidenceCohort Studyn=1044Pregnancy Discomfort

A Prospective Cohort Study on the Impact of Reflexology in Patients With Breast Cancer Using the MYCaW Scale

Kapila Ayush K, Herd Allison, Knife Natalie, Chaplin Pauly, Patel AshrafClinical breast cancer2019

Breast cancer treatment and recovery remain physically and psychologically challenging for patients. Reflexology has been studied as a complementary therapy to help relieve patients of the physical and psychological stresses involved with breast cancer. As a result of recent positive evidence, we studied its effects quantitatively from 2015 to 2016. Fifty-two patients completed pre- and post-reflexology intervention 'Measure Yourself Concerns and Wellbeing' (MYCaW) questionnaires. Patients were subdivided into breast cancer (BC) and non-breast cancer (NBC) groups. Concerns raised were subdivided in subcategory groups as per MYCaW guidelines and analyzed for improvements in each domain. Thirty (57.7%) patients in the BC group and 22 (42.3%) patients in the NBC group were analyzed. In the BC group, there was a 46.2% improvement in patients' concerns, and in the NBC group, a 41.4% improvement in concerns were noted. Overall, the symptoms improved by 44.2% (P < .0001). There was an improvement of 43.4% in patient well-being in the BC group, and a 37.8% change in the NBC group, signifying a total improvement in well-being of 41.2%. There was an improvement of 46.4% in the MYCaW scores; 46.4% in the BC group and 42.6% in the NBC group, signifying a combined average improvement of 42.4%. Patients with poor energy level, sleep problems, stress and tension, and hot flushes and sweats experienced the most improvement in their concerns. Our findings show that reflexology has significantly improved patient-reported outcomes using the MYCaW scale. These findings are encouraging and reflect that increased attention to strategies focusing on improving psychological well-being can help patients in managing their symptoms.

moderate evidenceCohort Studyn=52InsomniaCancer Pain Management

Integrative Oncology.

Gabriel Lopez, Jun J Mao, Lorenzo CohenThe Medical clinics of North America2017

The study examined the effects of integrative oncology approaches on the health of cancer patients and their caregivers. It found that these methods can help relieve symptoms related to cancer and its treatment, improving both physical and psychosocial health. This is important as it supports the idea that combining conventional treatments with complementary therapies can enhance overall patient well-being.

moderate evidenceCohort StudyCancer Pain Management

Symptom management and self-care for peripheral neuropathy in HIV/AIDS

Nicholas P K, Kemppainen J K, Canaval G E, Corless I B, Sefcik E F, Nokes K M, Bain C A, Kirksey K M, Eller L Sanzero, Dole P J, Hamilton M J, Coleman C L, Holzemer W L, Reynolds N R, Portillo C J, Bunch E H, Wantland D J, Voss J, Phillips R, Tsai Y-F, Mendez M Rivero, Lindgren T G, Davis S M, Gallagher D MAIDS care2007

Peripheral neuropathy is the most common neurological complication in HIV and is often associated with antiretroviral therapy. As part of a larger study on self-care for symptoms in HIV disease, this study analyzed the prevalence and characteristics of peripheral neuropathy in HIV disease, sociodemographic and disease-related correlates and self-care strategies. A convenience sample of 1,217 respondents was recruited from data collection sites in several US cities, Puerto Rico, Colombia and Taiwan. Results of the study indicated that respondents with peripheral neuropathy (n=450) identified 20 self-care behaviors including complementary therapies, use of medications, exercise and rest and/or elevation of extremities. Ratings of frequency and effectiveness were also included. An activities checklist summarized into five categories of self-care behaviors including activities/thoughts, exercise, medications, complementary therapies and substance was used to determine self-care behaviors. Taking a hot bath was the most frequent strategy used by those with peripheral neuropathy (n=292) and received the highest overall rating of effectiveness of any self-management strategies included in this study at 8.1 (scale 1-10). Other self-care strategies to manage this symptom included: staying off the feet (n=258), rubbing the feet with cream (n=177), elevating the feet (n=236), walking (n=262), prescribed anti-epileptic agent (n=80), prescribed analgesics (n=84), over-the-counter medications (n=123), vitamin B (n=122), calcium supplements (n=72), magnesium (n=48), massage (n=156), acupuncture (n=43), reflexology (n=23) and meditation (n=80). Several behaviors that are often deemed unhealthy were included among the strategies reported to alleviate peripheral neuropathy including use of marijuana (n=67), cigarette smoking (n=139), drinking alcohol (n=81) and street drugs (n=30).

moderate evidenceCross-Sectionaln=1217Peripheral Neuropathy

Prevalence and predictors of complementary and alternative medicine/non-pharmacological interventions use for menopausal symptoms within the UK Collaborative Trial of Ovarian Cancer Screening

Gentry-Maharaj A, Karpinskyj C, Glazer C, Burnell M, Bailey K, Apostolidou S, Ryan A, Lanceley A, Fraser L, Jacobs I, Hunter M S, Menon UClimacteric : the journal of the International Menopause Society2017

The negative publicity about menopausal hormone therapy (MHT) has led to increased use of complementary and alternative medicines (CAM) and non-pharmacological interventions (NPI) for menopausal symptom relief. We report on the prevalence and predictors of CAM/NPI among UK postmenopausal women. Postmenopausal women aged 50-74 years were invited to participate in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). A total of 202 638 women were recruited and completed a baseline questionnaire. Of these, 136 020 were sent a postal follow-up-questionnaire between September 2006 and May 2009 which included ever-use of CAM/NPI for menopausal symptom relief. Both questionnaires included MHT use. A total of 88 430 (65.0%) women returned a completed follow-up-questionnaire; 22 206 (25.1%) reported ever-use of one or more CAM/NPI. Highest use was reported for herbal therapies (43.8%; 9725/22 206), vitamins (42.6%; 9458/22 206), lifestyle approaches (32.1%; 7137/22 206) and phytoestrogens (21.6%; 4802/22 206). Older women reported less ever-use of herbal therapies, vitamins and phytoestrogens. Lifestyle approaches, aromatherapy/reflexology/acupuncture and homeopathy were similar across age groups. Higher education, Black ethnicity, MHT or previous oral contraceptive pill use were associated with higher CAM/NPI use. Women assessed as being less hopeful about their future were less likely to use CAM/NPI. One in four postmenopausal women reported ever-use of CAM therapies/NPI for menopausal symptom relief, with lower use reported by older women. Higher levels of education and previous MHT use were positive predictors of CAM/NPI use. UKCTOCS Trial registration: ISRCTN22488978.

moderate evidenceCross-Sectionaln=88430Menopause SymptomsPregnancy DiscomfortCancer Pain Management

Use of complementary and alternative medicine in Denmark among women with and without breast cancer: a cross-sectional study

Benameur Elias, Olsen Anja, Rosthøj Susanne, Tjønneland Anne, Bidstrup Pernille E, Kyrø CecilieScandinavian journal of public health2025

The study aim was to describe the use of complementary and alternative medicine (CAM) among women with breast cancer and without breast cancer in Denmark. Furthermore, the aim was to investigate whether use was related to lifestyle factors, socioeconomic factors, comorbidities, and health-related quality of life (HRQoL). A cross-sectional design was applied, and data from 1452 women aged 63-82 years collected in 2010-2011 from the Danish Diet, Cancer, and Health cohort was used. Some 717 of the women had breast cancer and 735 were without breast cancer. Multivariable logistic regression was applied with CAM use as the outcome variable and lifestyle factors, socioeconomic factors, comorbidities, and HRQoL as explanatory variables. Adjustments were made for potential confounders. CAM was used by 34.3% (95% CI [30.1, 37.7]) of the women without breast cancer and 38.6% (95% CI [35.1, 42.2]) of the women with breast cancer. The most frequently used CAMs were massage, acupuncture/acupressure, relaxation techniques, reflexology, medicinal tea, herbs and plant extracts, and most CAM users used a single modality. CAM users were more likely to be younger, divorced, and less likely to smoke. Breast cancer status, body mass index, alcohol use, and comorbidity status were not significantly associated with CAM use. CAM users had lower means across all HRQoL dimensions compared to non-users. CAM use is common among Danish women, with no significant difference found when comparing women with and without breast cancer. CAM users seemingly had lower HRQoL, and were more likely to be younger, divorced, and less likely to smoke.

moderate evidenceCross-Sectionaln=1452Cancer Pain Management

Prevalence of complementary/alternative medicines (CAMs) in a cancer population in northern Italy receiving antineoplastic treatments and relationship with quality of life and psychometric features

Saini Andrea, Berruti Alfredo, Capogna Serena, Negro Manuela, Sguazzotti Erica, Picci Rocco Luigi, Campagna Sara, Dongiovanni Vincenzo, Dogliotti Luigi, Furlan Pier Maria, Ostacoli LucaQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2011

To explore the use of CAM (Complementary/Alternative Medicine) in a population of cancer patients undergoing antineoplastic therapy, and to compare differences in sociodemographics, quality of life, and psychological features between CAM users and non-users. The study population was consecutive cancer patients undergoing antineoplastic treatment in three Piedmont cancer centers. Data were collected from anonymous questionnaires investigating CAM use or not, and what type if used, and sociodemographics, and through validated psychometric instruments to assess psychological features: Functional Assessment of Cancer Therapy-General, the Hospital Anxiety and Depression Scale, and the Mini Mental Adjustment to Cancer Scale. Of the 288 evaluable patients, 52 (18.1%) reported using one or more types of CAM; the most often cited were herbs, special diets and body-based practices, such as plantar reflexology, chiropractic application, and massage. On quality of life assessment, CAM users scored lower than CAM non-users for physical wellbeing (P = 0.006); no significant differences emerged for anxiety and depression and coping styles. CAM use is less prevalent in northern Italy than in most other European countries. CAM users were found to have a lower quality of life than CAM non-users.

moderate evidenceCross-Sectionaln=288Cancer Pain ManagementAnxietyDepression

Predictors of alternative and complementary medicine use in inflammatory bowel disease: do measures of conventional health care utilization relate to use?

Burgmann Twila, Rawsthorne Patricia, Bernstein Charles NThe American journal of gastroenterology2004

Alternative and complementary therapies (ACM) have gained increasing attention in the past few years. It was our purpose to determine whether increased ACM use is associated with increased use of conventional health care resources. Additionally, demographics of use, subjective benefit, and cost were analyzed. We enrolled 150 inflammatory bowel disease (IBD) patients from a tertiary care center and performed a phone survey of their ACM use in the past year. A population-based administrative database was accessed to extract data regarding use of conventional medicine (hospitalizations, doctor visits, and GI specific doctor visits). Patients were divided into three groups: (i) no ACM (n = 60) (ii) users of exercise, diet, and prayer (EDP) exclusively (n = 47) (iii) other ACM use (n = 43) which included those who may have used EDP as well as any of acupuncture, chiropractic, homeopathy, naturopathy, herbology, massage, relaxation, reflexology, hypnotherapy, aromatherapy, meditation, or support group. ACM was used by 60% (EDP 31%, other ACM 29%). There were no significant differences in use between the three groups by disease diagnosis, education level, employment status, use of IBD medications, number of hospitalizations, doctor visits, or GI specific doctor visits. The EDP group was more likely to be married (p = 0.006) and female (p = 0.04) compared to no ACM. The EDP group tended to be older than the no ACM (p = 0.001) and other ACM (p = 0.01). The other ACM had shorter disease duration than EDP (p = 0.04) and no ACM (p = 0.04). The most commonly used therapies were diet (45%), herbal (17%), exercise (15%), prayer (11%), and relaxation (10%). ACM was sought for pain/cramps (64%), diarrhea (60%), and gas/bloating (21%). Seventy-three percent of EDP interventions incurred no cost compared to 33% with other ACM (p < 0.0001). The median annual amount spent on other ACM was $56 (range $0-$4800). Subjectively, patients felt helped by trials of EDP 95% of the time whereas

moderate evidenceCross-Sectionaln=150Crohn's Disease / Colitis

Complementary medicine use, views, and experiences: a national survey in England

Sharp Debbie, Lorenc Ava, Morris Richard, Feder Gene, Little Paul, Hollinghurst Sandra, Mercer Stewart W, MacPherson HughBJGP open2018

In 2005,12% of the English population visited a complementary and alternative medicine (CAM) practitioner. To obtain up-to-date general population figures for practitioner-led CAM use in England, and to discover people's views and experiences regarding access. A face-to-face questionnaire survey was commissioned. A nationally representative adult quota sample (aged ≥15 years) was used. Ten questions were included within Ipsos MORI's weekly population-based survey. The questions explored 12-month practitioner-led CAM use, reasons for non-use, views on NHS-provided CAM, and willingness to pay. Of 4862 adults surveyed, 766 (16%) had seen a CAM practitioner. People most commonly visited CAM practitioners for manual therapies (massage, osteopathy, chiropractic) and acupuncture, as well as yoga, pilates, reflexology, and mindfulness or meditation. Women, people with higher socioeconomic status (SES) and those in south England were more likely to access CAM. Musculoskeletal conditions (mainly back pain) accounted for 68% of use, and mental health 12%. Most was through self-referral (70%) and self-financing. GPs (17%) or NHS professionals (4%) referred and/or recommended CAM to users. These CAM users were more often unemployed, with lower income and social grade, and receiving NHS-funded CAM. Responders were willing to pay varying amounts for CAM; 22% would not pay anything. Almost two in five responders felt NHS funding and GP referral and/or endorsement would increase their CAM use. CAM use in England is common for musculoskeletal and mental health problems, but varies by sex, geography, and SES. It is mainly self-referred and self-financed; some is GP-endorsed and/or referred, especially for individuals of lower SES. Researchers, patients, and commissioners should collaborate to research the effectiveness and cost-effectiveness of CAM and consider its availability on the NHS.

moderate evidenceCross-Sectionaln=4862

Usage of alternative medical systems, acupuncture, homeopathy and anthroposophic medicine, by older German adults

Büssing Arndt, Ostermann Thomas, Heusser Peter, Matthiessen Peter FZhong xi yi jie he xue bao = Journal of Chinese integrative medicine2011

The manifold studies on the usage of complementary and alternative medicine (CAM) indicate that its utilization differs with respect to socio-cultural background, gender, age and underlying disease. This study intended to analyze the usage of specific CAM practices among a population of older German adults with health insurance coverage. Data of 5 830 older individuals who participated in an anonymous cross sectional survey among German insurance beneficiaries were analyzed with respect to usage of CAM treatments applied by medical doctors or non-medical practitioners within the last 5 years. The most frequently used approaches were acupuncture/traditional Chinese medicine (21%), homeopathy (21%), movement therapies/physical exercises (19%), osteopathy/chiropractic (12%), herbs/phytotherapy (7%), diets/specific food recommendations (6%) and foot reflexology (5%). Anthroposophic medicine was used only to a minor degree. Acupuncture and homeopathy users were likely to choose more than one CAM treatment simultaneously, particularly the combination of homeopathy and acupuncture. Moreover, this study can confirm significant differences between women and men in the use of the main relevant CAM interventions. The relative proportion of acupuncture usage was similar to homeopathy, which is an alternative whole medical system originating from Western Europe. This means that an Eastern alternative system is established also in Germany. In several cases not only one CAM treatment was used but distinct combinations existed (particularly homeopathy and acupuncture); thus one should be cautious to draw predictive conclusions from studies with broad and unspecific CAM categories, for among them there are several therapies which should not be regarded as CAM.

moderate evidenceCross-Sectionaln=5830

Usage of complementary medicine across Switzerland: results of the Swiss Health Survey 2007

Klein Sabine D, Frei-Erb Martin, Wolf UrsulaSwiss medical weekly2012

This study investigated the use among the Swiss adult population and regional dissemination of various methods of complementary medicine (CM) provided by physicians or therapists in Switzerland. Data of the Swiss Health Survey 2007 were used, which comprised a telephone interview followed by a written questionnaire (18,760 and 14,432 respondents, respectively) and included questions about people's state of health, health insurance and usage of health services. Users and non-users of CM were compared using logistic regression models. The most popular CM methods were homeopathy, osteopathy, acupuncture and shiatsu/foot reflexology. 30.5% of women and 15.2% of men used at least one CM method in the 12 months preceding the survey. Lake Geneva region and central Switzerland had more CM users than the other regions. Women, people between 25 and 64 years of age and people with higher levels of education were more likely to use CM. 53.5% of the adult population had a supplemental health insurance for CM treatments. 32.9% of people with such an insurance used CM during the 12 months preceding the survey, and so did 12.0% of people without additional insurance. Almost one fourth of the Swiss adult population had used CM within the past 12 months. User profiles were comparable to those in other countries. Despite a generally lower self-perceived health status, elderly people were less likely to use CM.

moderate evidenceCross-Sectionaln=18760

[The effect of self-foot reflexology on the relief of premenstrual syndrome and dysmenorrhea in high school girls]

Kim Yi-Soon, Kim Min-Za, Jeong Ihn-SookTaehan Kanho Hakhoe chi2004

This study was aimed to identify the effect of self-foot reflexology on the relief of premenstrual syndrome and dysmenorrhea in high school girls. Study subjects was 236 women residing in the community, teachers and nurses who were older than 45 were recruited. Data was collected with self administered questionnaires from July 1st to August 31st, 2003 and analysed using SPSS/WIN 10.0 with Xtest, t-test, and stepwise multiple logistic regression at a significant level of =.05. The breast cancer screening rate was 57.2%, and repeat screening rate was 15.3%. With the multiple logistic regression analysis, factors associated with mammography screening were age and perceived barriers of action, and factors related to the repeat mammography screening were education level and other cancer screening experience. Based on the results, we recommend the development of an intervention program to decrease the perceived barrier of action, to regard mammography as an essential test in regular check-up, and to give active advertisement and education to the public to improve the rates of breast cancer screening and repeat screening.

limited evidenceCross-Sectionaln=236Q3 JournalMenstrual CrampsPMS (Premenstrual Syndrome)Cancer Pain Management

Does reflexology work? Common questions

Is reflexology scientifically proven?

No. The most careful reviews conclude reflexology isn't a proven treatment for any specific medical condition. What the research more consistently supports is relaxation and short-term relief of anxiety and pain. We track 808 studies here, graded by evidence strength, so you can judge for yourself.

Does reflexology actually work?

It depends what you mean. For curing or treating a disease, the evidence doesn't support it. For helping people relax and feel less anxious or in less pain during a session, a number of small studies are positive, including 245 randomized controlled trials and 221 systematic reviews or meta-analyses in this library.

Is reflexology a pseudoscience?

Reflexology's core idea, that specific points on the feet map to distant organs, isn't backed by anatomy or physiology, and that's why critics call it pseudoscience. The relaxation and comfort people feel during a session are real, though. It's best understood as a complementary relaxation practice, not a medical treatment.

What is reflexology best supported for?

The strongest and most consistent evidence is for relaxation and short-term reduction in anxiety and pain, plus some cancer-care symptoms like nausea and fatigue. Evidence for treating specific diseases is weak. Use the evidence-strength filter to sort studies by how solid they are.

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