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Reflexology Research & Science

Does reflexology work? The honest answer from 808 peer-reviewed studies: the evidence is mixed and mostly early-stage. 245 are randomized controlled trials and 221 are systematic reviews or meta-analyses. The strongest signals are for relaxation, anxiety, and pain, not for curing disease. Every study is below, graded by evidence strength and pulled from PubMed.

808 studies · page 48 of 68

Facilitating comfort for hospitalized patients using non-pharmacological measures: preliminary development of clinical practice guidelines

Williams Anne M, Davies Anne, Griffiths GarethInternational journal of nursing practice2009

Nurses often use non-pharmacological measures to facilitate comfort for patients within the hospital setting. However, guidelines for use of these measures are commonly inadequate or absent. This paper presents 12 clinical practice guidelines that were developed from the findings of a literature review into non-pharmacological measures that are thought to facilitate patient comfort. The non-pharmacological measures addressed in these guidelines are: Aromotherapy, Distraction, Guided Imagery, Laughter, Massage, Music, Reiki, Heat or Cold, Meditation, Reflexology, Reposition and Transcutaneous Electrical Nerve Stimulation. These are preliminary guidelines for the use of non-pharmacological measures and further research and development of such guidelines is recommended.

preliminary evidenceSystematic ReviewQ2 Journal

Yoga for patients and carers in a palliative day care setting

McDonald Aileen, Burjan Elene, Martin SueInternational journal of palliative nursing2006

This study suggests that yoga can be of benefit to patients (and carers) in palliative care settings. Complementary therapies have been employed in our day care unit for several years--aromatherapy, reflexology and massage--and have grown in popularity, enabling relaxation and a feeling of well-being. For patients striving to remain physically fit and, in consultation with our physiotherapist, we felt there may be a role for a gentle form of yoga. A study of the literature yielded information on yoga and cancer but little evidence of its use in palliative care. Having identified a form of yoga that could be adapted for those with physical frailties-- Dru yoga--a 12-week pilot project was introduced into the day care unit. This proved to be highly successful and has now been incorporated as part of our therapeutic service.

preliminary evidencePilot StudyQ1 JournalCancer Pain Management

Does the experimental design capture the effects of complementary therapy? A study using reflexology for patients undergoing coronary artery bypass graft surgery

Gunnarsdottir Thora Jenny, Jonsdottir HelgaJournal of clinical nursing2007

Our purpose was to pilot test whether reflexology may reduce anxiety in patients undergoing Coronary Artery Bypass Graft Surgery in Iceland. Nurses need to study the effects of complementary therapies in general and particularly those that may be beneficial to decrease patients' anxiety. It has been assumed that reflexology lessens anxiety, but research is needed to substantiate such expectations. A pilot study using randomized design with experimental and control groups. Nine patients were recruited and randomly assigned into groups with five patients assigned into an experimental group receiving reflexology for 30 minutes and four patients into control group which rested for 30 minutes. Anxiety and physiological variables were measured pre- and post-reflexology sessions once a day over five days. The anxiety scores were lower for patients in the control group on all measures. Systolic blood pressure lowered significantly more in the control group than in the treatment group. No significant changes were observed for other variables. Patients' comments and responses overwhelmingly suggested increased well-being due to both experimental and control intervention. This study showed little evidence to support reflexology as a mean of reducing anxiety in CABG patients. Several methodological problems were identified that need to be considered further. It is suggested that reflexology should be tailored to individual needs and research methods used that allow for capturing its holistic nature. Further scholarly work is warranted to explore several methodological issues in studying complementary therapies in a highly complex treatment situation.

preliminary evidencePilot Studyn=9Q1 JournalHigh Blood Pressure

A pilot study to evaluate the effect of reflexology on mood and symptom rating of advanced cancer patients

Ross C S K, Hamilton J, Macrae G, Docherty C, Gould A, Cornbleet M APalliative medicine2002

Researchers tested whether reflexology could help advanced cancer patients feel better emotionally and manage their symptoms. This was an early-stage study designed to see if reflexology was worth studying more thoroughly in larger groups.

preliminary evidencePilot StudyQ1 JournalCancer Pain Management

Engaging Patients in Research That Involves Meditation: Religious Concerns and Nursing Implications

Lehto Rebecca H, Sikorskii Alla, Marshall Katherine, Wyatt GwenCancer nursing

Studies evaluating the use of meditative practices for supporting symptom management among patients undergoing cancer treatment have increased substantially in recent years. Although meditative practices as adjuncts to promoting health have become mainstream, concerns that such strategies conflict with traditional religious tenets have co-occurred. In the context of a 12-week sequential multiple assignment randomized trial of home-based meditative practices and reflexology delivered to patients with cancer by or with family caregivers to manage symptoms, early attrition was identified in the meditative practices arm. Finding religious concerns were factors contributing to attrition; the purpose is to describe adjustments to the training protocol for study recruiters and interveners when enrolling participants and teaching patient-caregiver dyads meditative practices. The training protocol for recruiters and interveners was adapted to address religious concerns related to meditative practices. Since initiation, recruiters and interveners have appreciated the adapted protocol, which has improved their capacity to respond to religious concerns. Participants have responded well to consideration of the practices as mindful movements coordinated with breath. Given broader application of meditation in symptom management studies, researchers will need to be ready to address religious concerns. It is essential that protocols for introducing meditation are broadly presented to respond to concerns of patients and cancer caregivers regarding perceived conflicts with their specific religious beliefs. As the provision of integrative care options that include meditation training for patients grows, nurses require awareness of potential barriers and strategies to ameliorate religious concerns.

preliminary evidencePilot StudyQ1 JournalCancer Pain Management

The role of complementary medicine in the holistic, patient-centered recovery from anorexia nervosa - a narrative review

Carvalho Isabel TJournal of complementary & integrative medicine2025

Anorexia nervosa (AN) can be a severe psychiatric disorder associated with one of the highest mortality rates among mental health conditions. AN treatment demands a comprehensive, multidisciplinary approach. However, conventional therapies often fall short in addressing the full biopsychosocial complexity of the illness. This narrative review explores the emerging role of complementary medicine (CM) in the management of AN, emphasizing its scientific rationale, clinical applications, and relevance within integrative care models. By synthesizing findings from current literature, the review examines a range of CM interventions, such as functional nutrition, dietary supplementation, phytotherapy, aromatherapy, acupuncture, reflexology, massage therapy, mindfulness meditation, yoga, Qigong, Tai Chi, homeopathy, and Bach Flower Remedies. These modalities aim to restore nutritional equilibrium, improve psychological well-being, enhance body image, reduce stress and anxiety, foster self-regulation, and strengthen the mind-body connection. When used alongside standard treatments, CM may offer a more holistic and individualized approach to care, supporting sustained recovery and reducing relapse risk. Nevertheless, while preliminary evidence is encouraging, further high-quality research is needed to validate the efficacy of these therapies and inform the development of evidence-based integrative treatment protocols for AN.

preliminary evidenceSystematic ReviewQ2 Journal

Evaluating foot reflexology as a proposed treatment for sensorineural hearing loss: A critical review

McClean Carina, Lucke-Wold BrandonWorld journal of clinical cases2025

This editorial critically evaluates the application of foot reflexology as a treatment for sensorineural hearing loss (SNHL) in infants, as proposed in a case report published in the World of Clinical Cases. SNHL is a condition characterized by damage to the cochlea or the neural pathways that transmit auditory information to the brain. The etiology of SNHL is often complex, involving genetic mutations, prenatal factors, or perinatal insults. Reflexology, an alternative therapy involving the application of pressure to specific points on the feet, is based on the hypothesis that these points correspond to different organs and systems in the body, including the auditory system. However, the biological plausibility and clinical efficacy of foot reflexology in addressing SNHL lack empirical support. This editorial examines the pathophysiology of SNHL, assesses the clinical claims of reflexology practitioners, and emphasizes the necessity of evidence-based approaches in treating infant hearing loss. While complementary therapies may provide ancillary benefits, they should not supplant validated medical treatments in managing SNHL in infants. Further research is needed to evaluate the safety and efficacy of foot reflexology and other alternative therapies in pediatric audiology.

preliminary evidenceSystematic ReviewQ2 Journal

Effects of foot reflexology on disease

He Ming-Ying, Ud Din M Jalal, Xu Hai-Feng, Wang Shang-Yu, Ying Guo-Huan, Qian Hao, Wu Bing, Qi Hong-Dan, Wang Xin, Zhang GangWorld journal of clinical cases2024

In this article, we review a recently published article to explore the significance of foot reflexology in modern medical practice. With the advancement of modern medicine, we are increasingly committed to finding the specific physiological mechanisms of foot reflexes to treat diseases, thereby better proving the therapy's effectiveness. It has been reported that foot reflexes can activate the cerebral cortex and organs corresponding to the feet, stimulating blood flow, nutrition and nerves through neural and endocrine regulation to achieve the purpose of treating and preventing diseases and promoting health. The therapy shows unique potential and value, and provides a new perspective on integrating traditional medicine and modern medicine.

preliminary evidenceSystematic ReviewQ2 Journal

A Pilot Study To Evaluate The Effect Of Reflexology On The Mood And Symptom Rating Of Advanced Cancer.

Ross, CSK, Hamilton, J., Macrae, G., Doherty, C., Gould, A. and Cornbleet, MA.Palliative Medicine2002

| Twenty-six patients with advanced cancer were given either reflexology or basic foot massage once weekly for six weeks. Two scales were used to assess mental and physical wellbeing. Both groups found the treatments pleasurable and relaxing, but no cumulative effect indicating the benefits of reflexology was found. Conclusion: | Reflexology and foot massage are pleasurable therapies that lead to temporary relaxation. In this study neither seemed to have a major effect on mood or common symptoms of patients with advanced cancer.

preliminary evidencePilot Studyn=26Q1 JournalCancer Pain Management

Evaluation of the effects of reflexology on quality of life and symptomatic relief in multiple sclerosis patients with moderate to severe disability; a pilot study.

L Miller, E McIntee, P MattisonClinical rehabilitation2014

Researchers tested whether reflexology could improve quality of life and reduce symptoms in people with moderate to severe multiple sclerosis disability. This was a small pilot study designed to explore whether reflexology might be helpful and to inform larger studies in the future.

preliminary evidencePilot StudyQ1 Journal

Effect of Foot Reflexology on Muscle Electrical Activity, Pressure, Plantar Distribution, and Body Sway in Patients with Type 2 Diabetes Mellitus: A Pilot Randomized Controlled Trial.

Thais Gebin Toledo, Larissa Alves Moreira Freire, Luciana Maria Dos Reis, Andréia Maria Silva Vilela Terra, Adriana Teresa Silva SantosInternational journal of environmental research and public health2022

This pilot study tested whether foot reflexology could improve muscle function, pressure distribution, and balance in people with type 2 diabetes. The researchers measured electrical activity in leg muscles, how pressure is distributed on the foot, and body sway (how stable people are when standing) before and after reflexology treatment.

preliminary evidencePilot StudyQ1 JournalDiabetes (Supportive)

The future of reflexology [Complementary Therapies in Nursing and Midwifery, 8, pp. 84-90, 2002]

Wilkinson I, Rayner C F JComplementary therapies in nursing & midwifery2003

This paper explores the future direction and potential of reflexology as a complementary therapy in nursing and midwifery practice. The authors discuss emerging opportunities and challenges for reflexology integration into healthcare settings based on current evidence and practice trends.

preliminary evidenceObservationalQ1 Journal

Does reflexology work? Common questions

Is reflexology scientifically proven?

No. The most careful reviews conclude reflexology isn't a proven treatment for any specific medical condition. What the research more consistently supports is relaxation and short-term relief of anxiety and pain. We track 808 studies here, graded by evidence strength, so you can judge for yourself.

Does reflexology actually work?

It depends what you mean. For curing or treating a disease, the evidence doesn't support it. For helping people relax and feel less anxious or in less pain during a session, a number of small studies are positive, including 245 randomized controlled trials and 221 systematic reviews or meta-analyses in this library.

Is reflexology a pseudoscience?

Reflexology's core idea, that specific points on the feet map to distant organs, isn't backed by anatomy or physiology, and that's why critics call it pseudoscience. The relaxation and comfort people feel during a session are real, though. It's best understood as a complementary relaxation practice, not a medical treatment.

What is reflexology best supported for?

The strongest and most consistent evidence is for relaxation and short-term reduction in anxiety and pain, plus some cancer-care symptoms like nausea and fatigue. Evidence for treating specific diseases is weak. Use the evidence-strength filter to sort studies by how solid they are.

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