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Reflexology and progressive muscle relaxation training for people with multiple sclerosis: a crossover trial

Authors: Mackereth Peter A, Booth Katie, Hillier Valerie F, Caress Ann-LouiseJournal: Complementary therapies in clinical practicePublished: February 1, 2009DOI: 10.1016/j.ctcp.2008.07.002
Q2 JournalSJR: 0.65h-index: 72SCImago
Moderate EvidenceRandomized Controlled Trialn=50 participants

In Plain Language: reflexology for high blood pressure, explained

To compare the effects of reflexology and progressive muscle relaxation training for people with multiple sclerosis, provided by nurse therapists, on psychological and physical outcomes. A crossover design was chosen with a 4-week break between treatment phases. The Short Form 36 and General Health Questionnaire 28 were completed by patients (n=50) pre and post each of the 6-week treatment phases. Salivary cortisol levels, State Anxiety Inventory, systolic and diastolic blood pressure and heart rate data were collected pre and post the weekly sessions. All of the chosen measures except for three SF-36 scales recorded significant changes, however, despite the 4-week break (washout period), most outcome measures did not return to their pre-treatment baseline levels. This meant that the analysis of the data was complicated by significant effects involving ordering of treatment occurring for eight of the variables (one from SF-36, two from the GHQ, SAI, Salivary Cortisol, Systolic BP and HR). However, there was a difference in the State Anxiety Inventory values between the treatments of the order of 1.092 units (95%CI 0.211-1.976) (p=0.016, Wilks lambda=0.885, df=1, 48) in favour of reflexology. Changes in salivary cortisol comparing levels pre 1st to post 6th session favoured reflexology (95%CI 0.098-2.644) (p=0.037, Wilks lambda=0.912, df=1, 48). A significant difference was found in the way the treatments affected change in systolic blood pressure following sessions; this favoured progressive muscle relaxation training (p=0.002, Wilks lambda=0.812, df=1, 48). Positive effects of both treatments following sessions and over the 6 weeks of treatment are reported, with limited evidence of difference between the two treatments, complicated by ordering effects.

Key Findings: what this randomised trial found about high blood pressure

  • ✓Both reflexology and progressive muscle relaxation training produced significant improvements on most psychological and physical outcome measures in people with multiple sclerosis.
  • ✓The 4-week washout period between treatment phases was insufficient to return most outcome measures to baseline levels, indicating sustained therapeutic effects.
  • ✓Treatment ordering effects were observed for eight variables, suggesting that the sequence of receiving reflexology versus progressive muscle relaxation influenced the results.

What This Means for You

If you have multiple sclerosis, reflexology may offer a slight advantage over progressive muscle relaxation for anxiety relief, though the evidence is moderate and individual results vary.

What This Means for Practitioners

This crossover trial provides evidence that reflexology can produce measurable improvements in state anxiety and salivary cortisol in MS patients, supporting its use alongside conventional therapies in clinical settings.

Study Design: how this randomised trial was run

Sample Size
50 participants
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Reflexology for high blood pressure: common questions

Does reflexology help with high blood pressure?

If you have multiple sclerosis, reflexology may offer a slight advantage over progressive muscle relaxation for anxiety relief, though the evidence is moderate and individual results vary.

What did this study find?

Both reflexology and progressive muscle relaxation training produced significant improvements on most psychological and physical outcome measures in people with multiple sclerosis. The 4-week washout period between treatment phases was insufficient to return most outcome measures to baseline levels, indicating sustained therapeutic effects. Treatment ordering effects were observed for eight variables, suggesting that the sequence of receiving reflexology versus progressive muscle relaxation influenced the results.

How strong is this evidence?

This is a randomised trial and we rate its evidence moderate. It covers 50 participants. It was published in Complementary therapies in clinical practice, a Q2 journal. Reflexology is a complementary therapy, not a replacement for medical treatment.

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