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Use of complementary and alternative medicine in Denmark among women with and without breast cancer: a cross-sectional study

Authors: Benameur Elias, Olsen Anja, Rosthøj Susanne, Tjønneland Anne, Bidstrup Pernille E, Kyrø CecilieJournal: Scandinavian journal of public healthPublished: August 20, 2025DOI: 10.1177/14034948251363843
Moderate EvidenceCross Sectionaln=1452 participants

In Plain Language: cancer pain, explained

The study aim was to describe the use of complementary and alternative medicine (CAM) among women with breast cancer and without breast cancer in Denmark. Furthermore, the aim was to investigate whether use was related to lifestyle factors, socioeconomic factors, comorbidities, and health-related quality of life (HRQoL). A cross-sectional design was applied, and data from 1452 women aged 63-82 years collected in 2010-2011 from the Danish Diet, Cancer, and Health cohort was used. Some 717 of the women had breast cancer and 735 were without breast cancer. Multivariable logistic regression was applied with CAM use as the outcome variable and lifestyle factors, socioeconomic factors, comorbidities, and HRQoL as explanatory variables. Adjustments were made for potential confounders. CAM was used by 34.3% (95% CI [30.1, 37.7]) of the women without breast cancer and 38.6% (95% CI [35.1, 42.2]) of the women with breast cancer. The most frequently used CAMs were massage, acupuncture/acupressure, relaxation techniques, reflexology, medicinal tea, herbs and plant extracts, and most CAM users used a single modality. CAM users were more likely to be younger, divorced, and less likely to smoke. Breast cancer status, body mass index, alcohol use, and comorbidity status were not significantly associated with CAM use. CAM users had lower means across all HRQoL dimensions compared to non-users. CAM use is common among Danish women, with no significant difference found when comparing women with and without breast cancer. CAM users seemingly had lower HRQoL, and were more likely to be younger, divorced, and less likely to smoke.

Key Findings: what this cross-sectional study found about cancer pain

  • ✓Complementary and alternative medicine (CAM) use was more prevalent among women with breast cancer (38.6%) compared to women without breast cancer (34.3%) in this Danish study of older women.
  • ✓The study examined associations between CAM use and multiple factors including lifestyle, socioeconomic status, comorbidities, and health-related quality of life among 1,452 women aged 63-82 years.
  • ✓Massage and acupuncture/acupressure were identified as the most frequently used types of complementary and alternative medicine among the study population.

What This Means for You

Reflexology is among the most commonly used complementary therapies in Denmark, but this study shows it's used equally by women with and without breast cancer, so it shouldn't be viewed as a cancer treatment.

What This Means for Practitioners

Reflexology is popular among older Danish women and typically used as a single therapy rather than combined with other modalities, suggesting clients view it as a standalone wellness practice.

Study Design: how this cross-sectional study was run

Sample Size
1452 participants
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Cancer pain: common questions

What does this study say about cancer pain?

Reflexology is among the most commonly used complementary therapies in Denmark, but this study shows it's used equally by women with and without breast cancer, so it shouldn't be viewed as a cancer treatment.

What did this study find?

Complementary and alternative medicine (CAM) use was more prevalent among women with breast cancer (38.6%) compared to women without breast cancer (34.3%) in this Danish study of older women. The study examined associations between CAM use and multiple factors including lifestyle, socioeconomic status, comorbidities, and health-related quality of life among 1,452 women aged 63-82 years. Massage and acupuncture/acupressure were identified as the most frequently used types of complementary and alternative medicine among the study population.

How strong is this evidence?

This is a cross-sectional study and we rate its evidence moderate. It covers 1,452 participants. It was published in Scandinavian journal of public health. This study is indexed here for context; it did not test reflexology itself.

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